Cromosomal damages proven!


As part of a comprehensive investigation of the potential genotoxicity of radiofrequency (RF) signals emitted by cellular telephones, in vitro studies evaluated the induction of DNA and chromosomal damage in human blood leukocytes and lymphocytes, respectively. The signals were voice modulated 837 MHz produced by an analog signal generator or by a time division multiple access (TDMA) cellular telephone, 837 MHz generated by a code division multiple access (CDMA) cellular telephone (not voice modulated), and voice modulated 1909.8 MHz generated by a global system of mobile communication (GSM)-type personal communication systems (PCS) cellular telephone. DNA damage (strand breaks/alkali labile sites) was assessed in leukocytes using the alkaline (pH>13) single cell gel electrophoresis (SCG) assay. Chromosomal damage was evaluated in lymphocytes mitogenically stimulated to divide postexposure using the cytochalasin B-binucleate cell micronucleus assay. Cells were exposed at 37±1°C, for 3 or 24 h at average specific absorption rates (SARs) of 1.0-10.0 W/kg. Exposure for either 3 or 24 h did not induce a significant increase in DNA damage in leukocytes, nor did exposure for 3 h induce a significant increase in micronucleated cells among lymphocytes. However, exposure to each of the four RF signal technologies for 24 h at an average SAR of 5.0 or 10.0 W/kg resulted in a significant and reproducible increase in the frequency of micronucleated lymphocytes. The magnitude of the response (approximately four fold) was independent of the technology, the presence or absence of voice modulation, and the frequency (837 vs. 1909.8 MHz). This research demonstrates that, under extended exposure conditions, RF signals at an average SAR of at least 5.0 W/kg are capable of inducing chromosomal damage in human lymphocytes.

Bioelectromagnetics 23:113-126, 2002. © 2002 Wiley-Liss, Inc.

Weitergeleitete Nachricht, erhalten von Herrn Dr. N. Cherry (über Roy Beavers, USA)
Mit freundlichen Grüßen übersandt Abgeordneten-Büro Volker Hartenstein

Answer by Neil Cherry

Subject: RE: Genotoxicity of Radiofrequency (RF) signals from cellphones

Date: Wed, 13 Feb 2002 08:46:38 +1300
Organization: Canterbury Regional Council

This paper in Bioelectromagnetics only reports significant micronuclei formation (strong evidence of genotoxicity) at 5W/kg and 10 W/kg. The implication is that only high exposures cause genetic damage. However, a genotoxic substance has a safe level of zero. Microwaves and cellphone radiation are genotoxic at non-thermals levels, e.g. Phillips et al, (1998) significant DNA strand breakage and repair (p<0.0001) at an SR of 0.0024W/kg. DNA damage leads to induced DNA repair and it is mistakes during repair that can lead to cancer and cell death. I have been through the Motorola funded paper of Malyapa et al which claim to show no DNA damage from 2450 MHz and cell phone radiation. In fact there data does show  significant DNA damage followed by repair, in a time sequence of length of  exposure. Look closely at the DNA sequence in this latest paper and it shows a jump in DNA damage followed by induced repair, confirming Phillips and Malyapa.