Betreff: melatonin as missing hormonal link re human diseases...5/2006
Datum: Tue, 29 May 2007 10:49:07 EDT

This study out of Paris does not confirm the "melatonin hypothesis....."    They need to review the recent info re ASTM Gene re melatonin synthesis and we need to know whether "close, chronic, prolonged nighttime exposures"  were properly evaluated.    The "lack of such focus,"  is the most likely explanation for the inability to confirm the "melatonin hypothesis......"     Take care  -  Joanne
Joanne C. Mueller
Guinea Pigs R Us
731 - 123rd Avenue N.W.
Minneapolis, Minnesota  55448-2127 USA
Phone:   763-755-6114
Email:  (5-29-07)

"Our frame of reference determines what we look at and how we look. And as a consequence, this determines what we find."    Burke J, The Day the Universe Changed, 1985.


1: Cancer Causes Control. 2006 May;17(4):547-52.Click here to read  Links

Is melatonin the hormonal missing link between magnetic field effects and human diseases?

Faculte de Medecine Pitie-Salpetriere, Service de Biochimie et Biologie Moleculaire, 91 bouleavrd de l'Hopital, 75013, Paris, France.

The disruption of melatonin secretion has been largely studied since it could provide the missing link between the exposure to 50/60-Hz electric and magnetic fields (EMF) and the occurrence of possible health effects as the "melatonin hypothesis". We analysed the current experimental data from animal (rodents) where contradictory results have been observed, and from human studies conducted with volunteers or with workers in various conditions of exposure, biological endpoints and metrics. In humans, even in long lasting exposures, the overall results of these studies do not support the "melatonin hypothesis". It is unlikely that malignancies or mood disorders reported by people exposed to 50/60-Hz EMF could be related to the disruption of the melatonin levels.

PMID: 16596309 [PubMed - indexed for MEDLINE]